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EMR Literature Survey - February 2008
By: Takebayashi T et al
Published in: Br J Cancer. 2008 Feb 12;98(3):652-9.
INTERPHONE case-control study in Japan of brain tumours in relation to mobile phone use. Subjects included 88 patients with glioma, 132 with meningioma, and 102 with pituitary adenoma and 683 individually matched controls. Exposure assessment included a questionnaire on mobile phone use as well as estimation of the specific absorption rate (SAR) inside the tumour, taking account of spatial relationships between tumour localisation and intracranial radiofrequency distribution. The adjusted odds ratios (ORs) for regular mobile phone users being 1.22 (95% confidence interval (CI): 0.63-2.37) for glioma and 0.70 (0.42-1.16) for meningioma. When the maximal SAR value inside the tumour tissue was accounted for in the exposure indices, the overall OR was again not increased and there was no significant trend towards an increasing OR in relation to SAR-derived exposure indices. The authors noted that a non-significant increase in OR among glioma patients in the heavily exposed group may reflect recall bias.
By: Sadetzki S et al
Published in: Am J Epidemiol. 2008 Feb 15;167(4):457-67.
INTERPHONE case-control study in Israel of parotid gland tumors (PGTs) in relation to mobile phone use. Subjects included 402 benign and 58 malignant incident cases of PGTs and 1,266 population individually matched controls. Exposure was assessed via a questionnaire of mobile phone use. For all the subjects, no increased risk of PGTs was observed for ever having been a regular cellular phone user (odds ratio, OR = 0.87; p = 0.3) or for any other measure of exposure investigated. However, for ipsilateral use, the ORs in the highest category of cumulative number of calls and call time without use of hands-free devices were 1.58 (95% confidence interval, 95% CI: 1.11- 2.24) and 1.49 (95% CI: 1.05- 2.13), respectively. The risk for contralateral use was not significantly different from unity. The authors conclude that the results suggest an association between mobile phone use and PGTs.
These two studies form part of the INTERPHONE project which is a multi-national series of epidemiological studies (from 13 different countries) testing whether using mobile phones increases the risk of various cancers in the head and neck. The project is coordinated by the International Agency for Research on Cancer (IARC), an agency of the World Health Organisation (WHO). Further information on the project is available from the IARC website at http://www.iarc.fr/en/research-groups/RAD/RCAd.html The INTERPHONE studies are based on a common core protocol to enable valid data pooling. A comprehensive protocol for the INTERPHONE project is available at: http://www.iarc.fr/en/research-groups/RAD/INTERPHONEStudyProtocol.pdf. Results from a pooled analysis of all the studies are expected at a later stage.
By: Leitgeb N
Published in: Wien Med Wochenschr. 2008 Jan;158(1-2):36-41.
This paper discusses the issue of whether precaution should be applied to mobile phone use by children
By: O'Carroll MJ and Henshaw DL
Published in: Risk Anal. 2008 Feb;28(1):225-34.
The authors compare the IARC (2002) and CDHS (2002) reviews of extremely low frequency electric and magnetic fields and possible health effects which reached partly different conclusions from similar epidemiological evidence.
By: Djeridane Y et al
Published in: Radiat Res 2008 Mar;169(3):337-43
Study investigating the effect of exposure to mobile phone radiofrequency radiation on steroid (cortisol and testosterone) and pituitary (thyroid-stimulating hormone, growth hormone, prolactin and adrenocorticotropin) hormone levels in 20 healthy male volunteers. The authors report no apparent effect in endocrine functions in men.
By: Genuis SJ
Published in: Public Health. 2008 Feb;122(2):113-24.
Review of the scientific literature and recommendations relating to the link between electromagnetic radiation and human health.
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