Occupational exposure to extremely low frequency magnetic fields and risk of Alzheimer disease

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This was a systematic review and meta-analysis of 14 case-control and 8 cohort studies. The study investigated the relationship between Alzheimer’s disease and occupational exposure to extremely low frequency magnetic fields (ELF MF). The exposure to participants was categorised by a job exposure matrix, which included specific jobs that were assigned an exposure level, based on the work history of the participants. The authors reported an association between occupational exposure to ELF MF and Alzheimer’s disease (Risk Ratio (RR) 1.63; 95% confidence interval (CI): 1.35 – 1.96). The differences between gender was also examined with females having a higher RR (RR of 2.39 and 95% CI of 1.29 – 4.40) than males (RR of 1.50 and 95% CI of 1.22 – 1.85). There was moderate to high inconsistency between the studies included, which could indicate limitations of the methods. The meta-analysis also reported indications of publication bias, where papers showing effects are more likely to be published. The authors concluded that occupational exposure to ELF MF may increase the risk of Alzheimer’s disease. However, the authors suggest that this conclusion should be taken with caution due to the limitations of the research in the area.

Occupational exposure to extremely low frequency magnetic fields and risk of Alzheimer disease: A systematic review and meta-ana

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Some epidemiological studies observing outcomes from exposure to ELF MF have shown an association with Alzheimer’s disease. However, this association has not been established by consistent scientific evidence. This is reinforced by the current study, which also demonstrates the inconsistencies in the literature. The 2015 SCENIHR review assessed the impact of ELF MF on Alzheimer’s disease and indicated the need for further research.