Radiation literature survey

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p>This human provocation study investigated the effect of mobile phone on electrical cardiac activity. In the study, the heart rate and electrocardiogram (ECG) of one hundred healthy volunteers were recorded in three situations: without mobile phone, mobile phone switched on but not ringing, and mobile phone ringing (35 minutes). In the latter two conditions, the mobile phone (2G, GSM 900/1800) was placed inside the left pocket-anterior chest wall. There was no statistically significant difference observed in heart rate and ECG. The authors concluded that mobile phones have no significant effect on the measured heart rate and electrical cardiac activity when placed in close proximity to the heart in healthy subjects.

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This is an animal study investigating the long term effects of chronic microwave radiation on cognitive function. Rats were either exposed or sham to 2.856 gigahertz (GHz) microwaves with the average power density level of 5, 10, 20 or 30 milliwatts per square centimetre (mW/cm2) for 6 minutes, three times a week for up to 6 weeks. The authors suggested that in the long-term, chronic microwave exposure could induce dose dependent deficit of spatial learning and memory in rats.

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p>This animal study investigated the effects of exposure to radiofrequency (RF) radiation on the blood-brain barrier (BBB) and cognitive changes in rats. A total of 108 male rats were exposed to RF at 900MHz, 1 mW/cm² or sham for 14 or 28 days (3 hours per day). The specific energy absorption rate (SAR) varied between 0.016 watts per kilogram (W/kg) for the whole body and 2 W/kg locally in the head. The authors found that the 28-day exposure impairs spatial memory and damages BBB permeability in rats.

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This study aimed at validating the mobile phone use history reported by study participants in a large Swedish population-based case-control study that investigated the association between mobile phone use and acoustic neuroma risk. The self-reported start year of mobile phone use was validated from a total of 96 out of 326 cases and 111 out of 505 controls, using the network operator data. About 60% of subjects were able to correctly identify the start year of mobile phone use. The authors concluded that recall bias could not be excluded in this study.

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One of the biggest problems with epidemiological studies investigating the relationship between mobile phone use and tumour risk is the validity of data on self-reported mobile phone use obtained from the study participants. Recall bias is often the cause and as cases over-report and controls under-report their mobile phone use, bias in results may occur and interpretation of results becomes difficult. The INTERPHONE project, which is a large case-control study looking into association between mobile phone use and cancer risks from 13 different countries including Australia, also cites that recall bias is one of the limitations of the study that prevent conclusions of causality being drawn. Interestingly, in this study there was no significant difference between cases and controls in estimating start year.

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The aim of this animal study was to investigate whether exposure to radiofrequency (RF) electromagnetic fields can cause behavioural changes. Mice were exposed to a 2.45 Gigahertz (GHz) RF field at 10-100 milliwatts for 60 min/day, up to 120 days. After the exposure, mice were assessed for anxiety, obsessive compulsive disorder (OCD) and depression-like behaviour. The authors concluded that up to 120 days of RF exposure does not cause any behavioural changes in mice.

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This is an animal study that looked into the effect of extremely low frequency (ELF) magnetic fields (MF) on behavioural, hormonal, and metabolic changes in rats. In the study, rats were exposed to a 0.1 mT magnetic field at frequencies of 1 and 5 Hertz (Hz), for a period of up to 21 days. ELF-MF exposure did not alter body weight, or food and water intake. There were different effects observed between the exposure at 1 and 5 Hz on two stress hormones. The exposure at 5 Hz also showed increased activities in dopamine-related behaviour. The authors concluded that the effects of ELF-MF on hormonal and behavioural responses may differ depending on the frequency and time of exposure.

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In animals, the possibility that exposure to ELF fields may affect neurobehavioral function has been explored by a number of different studies and these have been reviewed by the World Health Organization (WHO, 2007). The review by WHO found no consistent effects of ELF fields in stress-related hormones of the pituitary-adrenal axis in mammals, with the possible exception of transient (minutes duration) stress following the onset of ELF electric field exposure at levels significantly above perception thresholds. Furthermore most studies that investigated the effects of ELF fields in hormones involved in controlling metabolic activity found no effect.

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This is an in vitro study that investigated whether ELF magnetic fields resulting from electricity use can affect several cellular functions, such as cell proliferation and apoptosis. Mouse embryonic fibroblasts (MEF) were exposed to 50 Hz ELF magnetic fields at 2 mT for 0.5h, 2h, 6h, 12h, and 24h. The authors found significant increases in some cellular and molecular mechanisms.

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This is a pooled analysis of all the epidemiological studies investigating the association between mobile phone use and brain cancer. The authors report a reduced cancer risk (odds ratio = 0.8).They found that individual study design causes the major difference in published results among the studies. The authors concluded that the results of the pooled analysis support reassuring rather than alarming conclusions on long-term health risks from mobile phone use.

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This animal study investigated the effects of exposure to third generation (3G) mobile phone to the parotid gland of rats. Rats were exposed to a 2100 megahertz (MHz) 3G RF signal, at a specific absorption rate of 0.4 Watts per kilogram, for 6 hours/day, 5 days/week, for 10 or 40 days. The parotid glands were analysed for histopathological and biochemical changes. The two exposure groups showed numerous histopathological changes and more prominent in the 40-day exposed group. The cell size between the exposed group and the control group showed statistically significant difference. The authors concluded that exposure to 2100 MHz RF radiation causes salivary gland damage to some extent and especially with longer exposure duration.

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This in vitro study investigated whether exposure to extremely low frequency magnetic fields (at 1.5 microtesla) affects the cell growth of human epidermal keratinocytes. The authors found that two different types of epidermal keratinocytes responded to ELF magnetic fields differently, after simultaneous exposure, i.e. ELF exposure affected one type of cell but not the other. The authors suggested that the biological effects of ELF magnetic fields in epidermal keratinocytes are cell type specific.

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