Radiation literature survey
The radiation literature survey provides updates on published literature related to radiation (both ionising and non-ionising) and health.
Published literature includes articles in peer-reviewed scientific journals, scientific-body reports, fact sheets, conference proceedings etc.
The updates on new radiation literature that are of high quality and of public interest will be published as they arise. For each update, a short summary and a link to the abstract or to the full document (if freely available) are provided. The update may also include a commentary from ARPANSA and links to external websites for further information. The links may be considered useful at the time of preparation of the update however ARPANSA has no control over the content or currency of information on external links. Please see the ARPANSA website disclaimer.
Explanations of the more common terms used in the updates are found in the glossary.
The radiation literature that is listed in the updates is found by searching various databases and is not exhaustive.
The intention of the radiation literature survey is to provide an update on new literature related to radiation and health that may be of interest to the general public. ARPANSA does not take responsibility for any of the content in the scientific literature and is not able to provide copies of the papers that are listed.
Visit the National Library of Australia Australian Government Web Archive to access archived information no longer available on our website.
Effects of 1950 MHz W-CDMA-like signal on human spermatozoa
Nakatani-Enomoto S et al
Bioelectromagnetics 2016: in press
This is an in vitro study that investigated the non-thermal effects of RF radiation on sperm. Sperm samples were collected from a total of 55 participants aged 20-44 years. Sperm cells were subjected to RF exposure at a frequency of 1950 megahertz (MHz) and at specific absorption rate (SAR) of 2 and 6 watts per kilogram (W/kg) and to sham, for 1 hour. The authors found that RF exposure did not have any effects on human sperm cells in a condition where the temperature is well-controlled.
Social behavioral testing and brain magnetic resonance imaging in chicks exposed to mobile phone radiation during development
Zhou Z et al
BMC Neurosci 2016; 17 (1): 36-
This animal study aimed to investigate whether RF radiation affects the development of embryos. A total of 76 developing chick embryos were divided into two groups: control and exposed. Eggs were exposed to RF emitted from a mobile phone operating at 900 MHz for 10 hours per day, for 16 days. The power flux density was up to 18 milliwatts per centimetre squared (mW/cm2) which is around 40 times above the public exposure limit in the Australian RF Standard. After hatching, it was found that in the exposed group the chick social behaviours were impaired and the development of the cerebellum appeared to be delayed. The authors concluded that prenatal RF exposure could have an adverse effect on brain development.
Has the incidence of brain cancer risen in Australia since the introduction of mobile phones 29 years ago?
Chapman S, Azizi L, Luo Q, Sitas F
Cancer Epidemiol 2016: in press
This ecological study compared mobile phone ownership with the incidence of brain cancer in Australia. In the study, brain cancer incidence rates from 1982 to 2012 are compared with the number of mobile phone accounts in the Australian population from 1987 to 2012. The percentage of the population having mobile phone accounts increased from 0% in 1987 to 94% in 2014. During the 30 year period age-adjusted (adult) brain cancer incidence rates increased slightly in males but were stable in females. Significant increases in brain cancer incidence were observed only in the elderly (aged ≥ 70 years), but the increase in incidence in this age group began from 1982, before the introduction of mobile phones. The study also modelled the expected incidence assuming risk estimates of 1.5 in ever-users of mobile phones, and 2.5 in a proportion of 'heavy users', assuming a 10 year latency period between use and incidence of brain cancer. The authors concluded that after nearly 30 years of mobile phone use in Australia among millions of people, there is no evidence of any rise in any age group that could be plausibly attributed to mobile phones.
There have been a number of ecological studies internationally that have compared the incidence of brain cancer with the number of mobile phone accounts over time. In Australia, Dobes et al (2011a, 2011b) reported no overall increase in the incidence of brain tumours between 2000-2008 in New South Wales and the Australian Capital Territory. There was, however, a significant increase in malignant brain tumours which was largely due to an increase in the ≥ 65-year age group, consistent with the Chapman et al results. Although the Chapman study does not investigate brain cancer sub-types it mentions that 80% of all brain cancers are gliomas.
The ecological studies on mobile phone use and brain cancer have been evaluated by a number of recent authoritative reviews (IARC, 2013 (PDF 6.1 mb); ARPANSA, 2014; SCENIHR, 2015 (PDF 5.1 mb)). Overall, as pointed out by the SCENIHR review, the ecological studies consistently show little indication of an increase in the age groups of most active mobile phone users and steady weak increases only in the elderly. It must be noted that overall these ecological studies are limited in many ways and provide the least evidence for a causal association.
Similar to the Chapman study, two previous studies have modelled the data to predict the expected brain tumour rates assuming increased risk estimates between mobile phone use and brain tumour (Deltour, 2012; Little 2012). Similar to the Chapman study, the previous studies showed that if the increased risk estimates were true than one would expect a much higher brain tumour incidence than what is currently observed.
Some case-control studies have reported possible associations between heavy mobile phone users and brain tumour. Based largely on this limited evidence the International Agency for Research on Cancer has classified radiofrequency fields as possibly carcinogenic to humans. More rigorous long-term studies are being coordinated by the World Health Organization and Australia is taking part in this research program.
Report of Partial Findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation in Hsd: Sprague Dawley SD Rats (Whole Body Exposure)
United States National Toxicology Program
United States National Toxicology Program
The National Toxicology Program (NTP) in the US is currently conducting a series of radiofrequency (RF) cancer studies in rats. The current report presents partial findings from the overall project, specifically looking at brain and heart cancer (glioma and schwannoma). In the study rats were exposed in utero and continuing throughout their lifetimes to GSM or CDMA RF at 900 megahertz (MHz), for 18 hours/day (10 minutes on/10 minutes off), 7 days/week, at a whole-body specific absorption rate (SAR) of 0 (sham), 1.5, 3, or 6 W/kg. The report found that the incidence of glioma in the brain and schwannoma in the heart of male rats exposed to RF from both CDMA and GSM type mobile phone systems was generally comparable with baseline incidence apart from schwannoma in the heart for male rats exposed to CDMA at 6 W/kg. The report concludes that these findings appear to support the International Agency for Research on Cancer classification of RF as a possible carcinogen.
There have been a number of animal studies that have investigated whether exposure to RF from mobile phones causes cancer (ICNIRP, 2013; SCENIHR, 2013). Overall a considerable number of well-performed animal studies have not shown mobile phone RF to cause cancer.
The conclusion of the current NTP report does not reflect the results reported which showed only one statistically significant association from the multiple endpoints tested which was schwannoma in the heart for male rats exposed to CDMA at 6 W/kg. It is important to note that this level of exposure is three times the SAR limit of 2 W/kg for the general public in the Australian Standard.
All other endpoints that were reported were not statistically significant and fell within the historical baseline incidence for these diseases in all animals from all studies undertaken by the NTP.
Childhood leukaemia and distance from power lines in California: a population-based case-control study
Crespi CM, Vergara XP, Hooper C, Oksuzyan S, Wu S, Cockburn M, Kheifets L
Br J Cancer 2016: in press
This case-control study investigated the association between ELF MF exposure and two childhood cancers (leukaemia and cancer of the central nervous system, CNS). There was a non-significant, slightly increased risk associated with living within 50 metres (m) of high voltage power lines and childhood leukaemia (odds ratio, OR = 1.4, 95% confidence interval, 95% CI = 0.7, 2.7). There was no evidence of increased risk for childhood leukaemia at distances beyond 50 m or CNS cancer at any distance. The authors concluded that there is at most weak support for increased risk of childhood leukaemia for children living within 50 m of high voltage power lines.
Measuring personal exposure from 900MHz mobile phone base stations in Australia and Belgium using a novel personal distributed exposimeter
Bhatt CR et al
Environ Int 2016; 92 : 388 - 397
This measurement study investigated the environmental exposure from mobile phone base stations. The RF exposure from GSM mobile phone base stations operating in the 900 MHz band in 34 different environments in Australia and Belgium were measured using a personal dosimeter and compared (in terms of electric fields). The study found that personal exposures in urban environment were higher than rural or suburban environments. The exposure levels in city centre, bus, and railway station in urban environment were among the locations associated with highest personal exposures in Australia. The exposure levels in most environments were however significantly lower in Australia compared to Belgium. The authors reported that personal RF exposure levels in the Australian environment are well below the limits for the general public in the Australian RF Standard.
Recent Research on EMF and Health Risk: Eleventh report from SSM's Scientific Council on Electromagnetic Fields, 2016
SSM, Scientific Council on Electromagnetic Fields
SSM Reports of Swedish Radiation Safety Authority 2016(15): 1 – 112
This is a review by the Swedish Radiation Protection Authority (SSM) on scientific studies published from October 2014 to September 2015 that investigated electromagnetic fields (EMF) and health. For static fields, the new epidemiological studies confirm earlier studies that there is an association between magnetic resonance imaging (MRI) and acute effects. For extremely low frequency (ELF) fields, an association between childhood leukaemia and elevated level of ELF magnetic fields (MF) continutes to be observed, but a causal relationship has still not been established. For RF fields, a new large Norwegian study did not find that maternal mobile phone use during pregnancy causes adverse health effects on the mother’s reproductive health. Overall, the report by SSM did not reveal any new findings to support a causal association between EMF exposure and adverse health effects.
Associations of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk
Su L, Fei Y, Wei X, Guo J, Jiang X, Lu L, Chen G
Leuk Lymphoma 2016: in press
This is a meta-analysis of epidemiological studies investigating parental occupational exposure to extremely low frequency (ELF) magnetic fields (MF) and childhood leukaemia. The meta-analysis included data from one cohort and 11 case-control studies. The authors report that overall neither maternal nor paternal occupational ELF MF exposure was associated with childhood leukaemia. The majority of studies included in the meta-analysis assessed ELF MF exposure by classifying the occupation of the subjects (job title). In order to decrease the potential of misclassification of ELF MF exposure the authors recommend further studies with exposure assessment that includes measurements.
The World Health Organization reviewed the epidemiological studies investigating parental occupational exposure to ELF MF and childhood leukaemia in 2007 (WHO, 2007 (PDF 4.0 mb)). The WHO review concluded that studies on parental occupational exposure to ELF MF in the preconception period or during gestation are methodologically weak and the results are not consistent.
Studies published since the WHO review have been highlighted in previous monthly reports. These include a German case-control study by Hug et al (2009) which did not find an association between preconceptional parental ELF MF exposure and childhood cancer (November 2009 report). An Australian study by Reid et al also did not find an increased risk of leukaemia in offspring of parents with occupational exposure to ELF EMF (September 2011 report).
Mobile Phone Use and the Risk of Parotid Gland Tumors: A Retrospective Case-Control Study
Gulf J Oncolog 2016; 1 (20): 71 - 78
This case-control study investigated the association between mobile phone use and parotid gland tumours. A total of 26 cases and 61 controls (all from the same hospital) were recruited in the study. The information on mobile phone use was obtained via questionnaire. Participants were considered exposed if the daily mobile phone use was more than 1 hour. The authors reported a statistically significant association between mobile phone use and parotid gland tumours (odds ratio, OR = 2.93, 95% CI = 1.07 – 8.03). The authors however noted that the results need to be interpreted with caution due to the small sample size.
The effects of the duration of mobile phone use on heart rate variability parameters in healthy subjects
Ekici B et al
Anatol J Cardiol 2016: in press
This is a cross-sectional study that investigated whether mobile phone use affects heart rate variability. A total of 148 healthy participants were included in the study. Based on the duration of mobile phone use, the participants were categorised into four groups: less than 30 minutes per day (min/d), 30-60 min/d, more than 60 min/d and no mobile phone use. The cardiovascular function of the participants was assessed via electrocardiogram. The authors reported that the heart rate variability was significantly increased in the three groups who used mobile phones.